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Researchers from the Charlie Dunlop School of Biological Sciences, in collaboration with The Oxford Research Centre in the Humanities, reveal a powerful link between olfactory loss and inflammation in a staggering 139 medical conditions. This research—led by professor emeritus Michael Leon, and researchers Cynthia Woo and Emily Troscianko—emphasizes a little-known but potentially life-altering connection: the role our sense of smell plays in maintaining our physical and mental health. The study appears in Frontiers in Molecular Neuroscience .

Olfactory dysfunction, often dismissed as a minor inconvenience, may actually be an early sign of various neurological and bodily diseases, as indicated by this research. "The data are particularly interesting because we had previously found that olfactory enrichment can improve the memory of older adults by 226%," said Leon. "We now know that pleasant scents can decrease inflammation, potentially pointing to the mechanism by which such scents can improve brain health.



" This finding, he added, could hold key implications for mitigating symptoms and possibly even reducing the onset of certain diseases through therapeutic olfactory stimulation. The study delves into the methodical tracking of 139 medical conditions associated with both olfactory loss and heightened inflammation, uncovering insights into a shared pathway linking these factors. Olfactory loss, which often precedes conditions such as Alzheimer's and Parkinson's diseases, .

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