Harnessing the eye’s natural defenses, scientists explore innovative ways to boost antioxidants and reduce oxidative stress in the lens, offering new hope for cataract prevention and delayed surgery. Review: Minimizing Oxidative Stress in the Lens: Alternative Measures for Elevating Glutathione in the Lens to Protect against Cataract . Image Credit: ARZTSAMUI / Shutterstock In a review article published in the journal Antioxidants , researchers at the University of Auckland, New Zealand, have discussed potential cataract treatment strategies that utilize endogenous molecular machinery of the eye lens to increase the level of antioxidant glutathione in different lens regions.
Background Cataract is a leading cause of visual impairment and a potential cause of blindness worldwide. The major risk factors for cataract onset include advancing age, diabetes, and having vitrectomy surgery. Cataract surgery is highly effective in treating the condition and restoring vision.
It is the most commonly performed surgical procedure worldwide. However, such high demand often creates significant pressure on the healthcare system, resulting in lengthy waiting times for surgery. This highlights the need for developing alternative strategies to prevent or delay the onset of cataracts.
Global impact: Cataracts account for 51% of blindness worldwide, underscoring the potential global health impact of new antioxidant-based treatments. Oxidative stress contributes significantly to the development.
