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An extensive tumor genomic analysis of individuals with ovarian cancer, led by researchers from Huntsman Cancer Institute at the University of Utah (the U) and Emory University, revealed that Black women have nearly identical mutations to other previously studied populations. But researchers also found a few notable differences that may be clinically relevant. Our analysis shows the importance of researching different types of populations.

The molecular features that we discover in one patient group will allow us to find potential targets for drug therapies that will work for all patients and improve ovarian cancer health care for everyone." Jen Doherty, MS, PhD, co-principal investigator of the study and co-leader of the Cancer Control and Population Sciences Program at Huntsman Cancer Institute and professor of population health sciences at the U Ovarian cancer is often diagnosed in its later stages due to a lack of clear symptoms or an effective screening approach, according to the National Cancer Institute. Over 12,000 women are estimated to have died from the disease in 2024.



Extensive federal and private research has been devoted to understanding the causes and optimal treatment regimens for this deadly type of disease. The study included individuals between 20 to 79 years of age who had been diagnosed with high-grade serous ovarian cancer, the most common ovarian cancer. State-of-the-art tumor sequencing technology was used to discern tumor characteristics.

Molecular e.

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