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The Packers-49ers rivalry helped define the careers of Brett Favre and Aaron Rodgers during their time in Green Bay. Favre was 12-2 against San Francisco for the Packers, including a 4-1 record in the playoffs. Rodgers was 6-7 against San Francisco with a 0-4 record in the postseason.

Those are stats that matter in this classic NFC rivalry. Which brings us to Jordan Love. The Green Bay quarterback had 194 yards, two TDs, and two interceptions in the 24-21 loss to the 49ers in the NFC divisional playoffs last season.



Green Bay might own Chicago, but San Francisco is a different story. The Packers are 7-3, but those three losses are against playoff contenders in Philadelphia, Minnesota, and Detroit. San Francisco might be 5-5, but they are still in that weight class when healthy.

So, yeah, this is a gotta-have-it game for the Packers just as much as the 49ers, and Green Bay has won four of the past five regular-season meetings. That is the highlight of a week that also features the "Harbaugh Bowl" between the Chargers and Ravens. Each week, we will pick NFL matchups straight up and against the spread.

A look at our track record this season: Straight up: 113-52 (7-6 in Week 11) Against the spread: 94-65-6 (7-6 in Week 11) Here are our picks for Week 12: NFL HQ: Live NFL scores | Updated NFL standings | Full NFL schedule NFL picks, predictions for Week 12 Pittsburgh Steelers (-3.5) at Cleveland Browns Thursday, 8:20 p.m.

, Amazon Prime Is this a letdown game for Pittsburgh on a sh.

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