Gout is a painful form of arthritis that primarily affects the joints, leading to severe pain and swelling, particularly in the big toes, ankles, knees, and fingers. Traditionally attributed to poor lifestyle choices and dietary habits, a recent study led by Professor Tony Merriman from the University of Otago has shifted this perspective, highlighting the significant role genetics plays in the development of gout. The groundbreaking research analyzed genetic data from 2.
6 million individuals, including 120,295 diagnosed with gout. This extensive study has uncovered the genetic underpinnings of the condition, revealing that inherited factors are more critical in the formation of gout than previously acknowledged. The researchers identified a total of 377 genetic regions associated with gout, of which 149 had never been linked to the condition before.
Professor Tony Merriman, the senior author of the study, expressed optimism regarding its potential to reshape the understanding of gout. In a media release, he emphasized, “This study busted the myth that gout has anything to do with poor lifestyle choices or poor diet—it is a condition with genetic influence.” This revelation is particularly significant as there has long been a stigma associated with gout.
Many individuals feel embarrassed and believe their condition is a result of poor dietary habits , leading to shame and reluctance in seeking appropriate medical treatment. Such attitudes can exacerbate the condition, m.