Dengue vaccine trials for phase three have begun in India. HEre is all you need to know about the dengue vaccine. Updated: August 20, 2024 6:51 PM IST By Edited by Dengue cases have been on a significant rise in India.
Monsoon season entails several mosquito borne infection that may turn fatal when not treated timely. There is no guaranteed cure for dengue, but different treatment are processed as per the severity of the case. The ICMR and Panacea Biotec have initiated the first-ever phase three clinical trial for developing a dengue vaccine in India, the Union Health Ministry said.
India’s indigenous tetravalent dengue vaccine, DengiAll, has been developed by Panacea Biotec and the first participant in this trial was vaccinated on Wednesday at the Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak. “The initiation of this phase three clinical trial for India’s first indigenous dengue vaccine marks a critical advancement in our fight against dengue. It reflects our commitment to protecting our citizens from this pervasive disease and underscores India’s capabilities in vaccine research and development,” Union Health Minister J P Nadda said.
Key Developments about Dengue Vaccine “Through this collaboration between ICMR and Panacea Biotec, we are not only taking a step towards ensuring the health and well-being of our people but also reinforcing our vision of Atmanirbhar Bharat in the healthcare sector,” he said. Panacea Biotec, one of three Indian companies to receive the strain, is at the most advanced stage of development. The company has worked extensively on these strains to develop a full-fledged vaccine formulation and holds a process patent for this work.
Phase one and two clinical trials of the Indian vaccine formulation were completed in 2018-19, yielding promising results, the statement said. The trial, primarily funded by the ICMR with partial support from Panacea Biotec, is set to follow up with participants for two years. Denue: Major Health Concern Dengue is a major public health concern in India, ranking among the top 30 countries with the highest incidence of the disease.
The global incidence of dengue has been steadily increasing over the past two decades, with more than 129 countries reporting dengue viral disease by the end of 2023, according to the World Health Organisation (WHO). In India, approximately 75-80 per cent of infections are asymptomatic, yet these individuals can still transmit the infection through the bite of Aedes mosquitoes, the statement said. Among the 20-25 per cent of cases where symptoms are clinically apparent, children are at a significantly higher risk of hospitalisation and mortality.
In adults, the disease can escalate into severe conditions like dengue hemorrhagic fever and dengue shock syndrome, the statement said. For breaking news and live news updates, like us on or follow us on and . Read more on Latest on .
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