Ubiquigent Limited (“Ubiquigent”), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced a strategic partnership with Alleo Labs Corp. (“Alleo”), a pioneer in using artificial intelligence (AI) to develop new therapeutics for neurological diseases. The partnership will combine Alleo’s AI-based approach to developing novel therapeutics with Ubiquigent’s platform and expertise in the field of DUB focused drug discovery.

Financial details were not disclosed. Under the terms of the partnership, Ubiquigent will receive exclusive access to Alleo’s AI software, RubDUB, to accelerate its search for novel DUB-modulating compounds required for the development of DUB inhibitors, DUB-targeting PROTACs and DUB-Targeting Chimeras (DUBTACs). Alleo will gain access to Ubiquigent’s platforms and expertise to advance its in-house DUB-focused precision neuroscience programmes.

In addition to advancing their own internal in-house programmes, the partners will also work jointly with third parties seeking to develop DUB-modulating therapeutics. Ubiquigent is a respected partner in the DUB field, with an evolving track record in the development of novel DUB targeting compounds and as a provider of specialist drug discovery services to support the drug discovery programmes of its partners. Modulators of DUB activity represent an underexploited strategy for targeting previousl.