Two new cases of the mpox variant clade 1b detected in the UK are the first locally transmitted cases in Europe and the first outside Africa, the World Health Organization said Tuesday. The UK Health Security Agency (UKHSA) confirmed late Monday that the two new cases were household contacts of Britain's first case identified last week, bringing the country's total confirmed cases to three. The WHO warned that European states should be prepared for "rapid action" to contain the latest mpox variant, which spreads through close physical contact including sexual relations and sharing closed spaces.
The two cases are also the first to be locally transmitted outside Africa since August 2024, when the WHO declared the outbreak of the new variant an international public health emergency—its highest level of alarm. Those affected are under specialist care and the risk to the UK population "remains low", UKHSA said. The original case was detected after the person traveled to several African countries on holiday and returned to the UK on October 21.
The patient developed flu-like symptoms more than 24 hours later and, on October 24, started to develop a rash that worsened in the following days. Mpox, a viral disease related to smallpox, has two types, clade 1 and clade 2. Symptoms include fever, a skin rash or pus-filled blisters, swollen lymph nodes and body aches.
The WHO first declared an international public health emergency in 2022 over the spread of clade 2. That outbreak mostl.