Toddler, two, dies of rare genetic condition that killed her three-year-old brother - leaving their mother 'devastated' and 'absolutely broken'

Toddler, two, dies of rare genetic condition that killed her three-year-old brother - leaving their mother 'devastated' and 'absolutely broken' By Dan Woodland Published: 01:08 BST, 21 September 2024 | Updated: 01:23 BST, 21 September 2024 e-mail View comments A two-year-old with a rare genetic condition has died just three years after the same disease killed her three-year-old brother. Isabelle Cooper passed away on Thursday, a year after she was found to have the same type of genetic heart disorder as her brother Alexander, who also died as a result of the condition on Boxing Day 2021. Her mother Dr Emily Cooper, a lecturer at the University of Central Lancashire, announced the tragic news on X, saying her family was 'devastated' and 'absolutely broken' over the death of 'our beautiful Isabelle'.

The now mother-of-two has previously revealed how she was unaware of Alexander's condition until two years after his death. She later found out that Isabelle had the same disorder, known as the PPA2 mutation, and that her and Isabelle's father Darren Bowes were both carriers. Two-year-old Isabelle Cooper, who had a rare genetic condition, has died just three years after the same disease killed her three-year-old brother Isabelle Cooper passed away on Thursday, a year after she was found to have the same type of genetic heart disorder as her brother Alexander (pictured together) Her mother Dr Emily Cooper (pictured with Isabelle) announced the tragic news on X, saying her family was.