RIO DE JANEIRO (AP) — Arianne Risso worked every day to help her patients battle cancer. That made it all the more heart wrenching when her life — along with that of seven other doctors — ended abruptly after a plane tumbled from the sky in Brazil. She boarded the ill-fated flight Friday in the city of Cascavel, in Parana state, bound for Sao Paulo’s Guarulhos international airport.

It crashed in the city of Vinhedo, and footage of the ATR 72 twin-engine turboprop plunging while in a flat spin horrified people across Brazil. It smashed into the backyard of a home inside a gated community and transformed into a fiery wreck. All 62 people aboard were killed, among them the eight doctors, according to a statement from Parana’s Medical Council.

Risso and at least one colleague were headed for an oncology conference to sharpen their knowledge about a disease that kills tens of thousands of Brazilians every year. “They were people used to saving lives, and now they lost theirs in such tragic circumstances,” Parana Gov. Ratinho Júnior told journalists in Vinhedo on Friday, adding that he had friends on the doomed plane.

“It is a sad day.” Risso's cousin, Stephany Albuquerque, recalled in a phone interview that the two often played together when she was young. Even then, Risso wanted to become a doctor and, as she grew older, applied herself so intensively to her studies that she rarely went out on the town.

Medicine was her calling. “Arianne treated people who .