In a recent study published in The Journal of Nutrition , a group of researchers estimated dietary polyphenol intake in healthy adults and investigated its associations with gastrointestinal (GI) and systemic inflammation markers. Background Due to their antioxidant and anti-inflammatory properties, the intake of polyphenol-rich foods (polyphenols) may reduce systemic inflammation and cardiovascular risk factors. However, polyphenol absorption and metabolism vary based on their structure, with only 5-10% absorbed in the small intestine and the rest reaching the large intestine.
Here, polyphenols can influence gut health by suppressing inflammation, enhancing microbial diversity, and promoting short-chain fatty acid production. Given the complexity of their metabolism, absorption, and bioefficacy, further research is needed to fully understand the differential effects of various polyphenol types on GI and systemic inflammation. About the study The present study conducted a secondary analysis of data from the United States Department of Agriculture (USDA) Nutritional Phenotyping Study, an observational cross-sectional study performed between 2015 and 2019 with approval from the University of California, Davis Institutional Review Board.
The sample comprised 350 generally healthy adults aged 18 to 65 years with body mass indices ranging from 18.5 to 45 kg/m2, recruited from the Davis, California area and balanced across sex, age, and body mass index (BMI) categories. Participant.