Personalized weight loss programs in obese children are shown to reduce specific harmful lipids linked to heart disease and metabolic issues, offering a promising strategy for early intervention and long-term health benefits. Study: Lipid profiling identifies modifiable signatures of cardiometabolic risk in children and adolescents with obesity . Image Credit: Pixel-Shot / Shutterstock.
com A recent study published in the journal Nature Medicine assesses the lipid profiles of obese children and adolescents and their health implications. What is obesity? Obesity refers to the abnormal accumulation of fat in the body. Both genetic and acquired traits contribute to the etiology of obesity, with some studies suggesting that up to 67% of obesity is heritable.
Obesity in children may increase the risk of developing diabetes or prediabetes, hypertension, and metabolic dysfunction-associated steatotic liver disease (MASLD), the latter of which is present in 40% of obese children. Furthermore, obesity affects the lipidome, with higher total cholesterol (TC), low-density lipoprotein (LDL), and triglyceride (TG) levels often observed, in addition to lower healthy high-density lipoprotein (HDL) levels. The current study examined how lipid profiles and individual lipid levels among obese children and adolescents impacted their health, with a specific focus on insulin resistance, dyslipidemia, fatty liver, and cardiometabolic risk factors.
About the study The researchers conducted a lipid p.