Gamma hydroxybutyrate (GHB)-related deaths in Australia have risen sharply in the last decade with use of the "party drug" extending beyond the clubbing scene to a broader population, according to new research from the National Drug and Alcohol Center (NDARC), UNSW Sydney. The study, published in Drug and Alcohol Review , shows that the rate of death related to GHB use increased by an average of 44% each year from 2016 onwards. Lead author Professor Shane Darke said this "steep rise" was consistent with increases in GHB-related ambulance callouts and emergency department attendances in some Australian jurisdictions.

"In recent years, GHB use appears to have extended to a population more likely to have substance use problems and use other respiratory depressants," Professor Darke said. Using a national coronial database, the researchers identified 217 GHB-related deaths between 2001 and 2021 to determine population rates and whether there had been any changes in case characteristics over time. Two distinct periods emerged: a "stable period" from 2001–2015, and an "accelerated period" during 2016–2021.

On average, there were 3.4 deaths per year recorded during the "stable period," compared to 22.8 deaths per year during the "accelerated period.

" While the circumstances of deaths remained constant—most were due to accidental overdose —there was a notable shift in other case characteristics. For instance, the authors found that later cases were slightly older on average (.