Curcumin is well known for its widespread health benefits, particularly for its antioxidant and anti-inflammatory properties. A polyphenol (a chemical compound in plants that offers specific health benefits) found in turmeric, curcumin is primarily responsible for its vibrant yellow color and is widely used in Indian and Asian cuisines. The participants were tested at zero, three, six, nine, and 12 months for indicators of anti-atherogenic activity, including pulse-wave velocity (PWV), as well as several cardiometabolic risk factors including total cholesterol, triglycerides, and uric acid.

Levels of pro-inflammatory cytokines were recorded, as well as high-sensitivity C-reactive protein levels (to evaluate systemic inflammation). Levels of low-density lipoprotein cholesterol, small dense low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, and uric acid were likewise all significantly lower in the curcumin-treated group at three, six, nine, and 12 months. Measurements of waist circumference, total body fat, and visceral fat were significantly lower in the curcumin group than in the placebo group at the six-, nine-, and 12-month visits.

Insulin resistance was also significantly lowered in the curcumin-treated group. “Curcumin can interact with certain medications, including blood thinners (e.g.

, Warfarin) and anti-platelet medications (e.g., Clopidogrel).

This could increase bleeding risk. Curcumin might [also] interfere with the absorpt.