A study published in the journal PLOS ONE describes the effectiveness of pomegranate peel extract in restoring the skin microbiota homeostasis through its antimicrobial action against Staphylococcus aureus . Study: Staphylococcus aureus/Staphylococcus epidermidis from skin microbiota are balanced by Pomegranate peel extract: An eco-sustainable approach . Image Credit: artfotoxyz / Shutterstock Background The skin microbiota represents many microorganisms that live in equilibrium, establishing an interspecies balance of microbiota community.

The composition of skin microbiota depends on the body site, age, sex, and skin pH. The predominant microbial species of skin microbiota belong to the Staphylococcus, Corynebacterium, Streptococcus, and Propionibacterium genera. Staphylococcus epidermidis (S.

epidermidis) is the most reported Staphylococcus spp., and it plays a crucial role in maintaining microbial balance on the skin. In healthy skin microbiota, S.

hominis, S. lugdunensis, and S. epidermidis exert antimicrobial effects against the Gram-positive bacteria S.

aureus. Any perturbation of skin microbial homeostasis can lead to dysbiosis, which is characterized by a reduced abundance of beneficial microbes like S. epidermidis and an increased abundance of pathogenic microbes like S.

aureus. Skin microbiota dysbiosis has been found to be associated with various skin diseases, including acne , atopic dermatitis, folliculitis, and psoriasis. An increased abundance of S.

aureus has.