TORONTO and HAIFA, Israel, Aug. 15, 2024 (GLOBE NEWSWIRE) -- NurExone Biologic Inc. (TSXV: NRX), (OTCQB: NRXBF), (Germany: J90) (the “ ” or “ ”) is pleased to announce significant advancements in their manufacturing process of exosomes.
Exosomes, which are naturally released by cells, hold immense promise for regenerative medicine and they are at the heart of the Company’s innovative ExoPTEN product, which is being developed for the treatment of acute spinal cord injury and glaucoma. In a recent study, NurExone focused on ensuring that the Company’s exosome production process could consistently deliver reliable products. The study compared exosomes produced from bone marrow-derived mesenchymal stem cells (MSCs) from two different donors.
Despite a natural variability in the starting material, the exosomes showed consistent yields measured in concentration of exosomes (Fig. A) and similar size distribution (Fig. B), demonstrating the reliability of NurExone's production methods.
"The exosome production process must be stable to ensure the same quality of exosomes every time, even when the stem cell material comes from different donors," notes Dr. Noa Avni, Director of Research and Development at NurExone, and She continues, "our tests and analysis have clearly shown that this is possible using our proprietary technology, which will allow large-scale mass production without genetic manipulation". To ensure the exosomes are not only consistent but also effective at t.