Listen to Story In the age of antimicrobial resistance, a new study has found a promising compound that can work against the bacteria that causes tuberculosis, including its drug-resistance strains. This new compound has shown promising results against Mycobacterium tuberculosis, the bacteria responsible for tuberculosis, and the leading cause of bacterial disease-related deaths globally . The study was conducted in collaboration with researchers from the Shanghai Institute of Materia Medica, China and McGill University, Canada.
The researchers, who published their findings in the journal Microbiology Spectrum, said that since current tuberculosis treatments are outdated , require long durations, and face the growing issue of antibiotic resistance, this discovery offers hope for developing more effective anti-tuberculosis drugs. In search of new antibiotics effective against tuberculosis, the research team explored natural compounds known for their antimicrobial properties. One such compound, sanguinarine, is derived from a flowering plant native to North America.
Current tuberculosis treatments are outdated, require long durations, and face the growing issue of antibiotic resistance. (Photo: PTI) While sanguinarine has been used in alternative medicine, its toxicity has prevented it from being used as a treatment for humans. To overcome this limitation, scientists modified sanguinarine using medicinal chemistry techniques, resulting in a safer and more potent compound called.