Findings from a new mouse study indicate that elenolic acid, a natural compound found in olives, can significantly lower blood sugar levels and promote weight loss. This research suggests the potential for developing safe, inexpensive natural products for managing obesity and type 2 diabetes. Obese diabetic mice treated with elenolic acid showed improved blood sugar regulation and weight loss comparable to, or better than, current diabetic medications.

The study highlights the compound’s ability to induce metabolic hormone release in the gut, promoting satiety and reducing food intake. Researchers are now investigating the compound’s absorption, distribution, metabolism, and excretion to ensure its safety for future clinical trials. New research from a mouse study indicates that elenolic acid , a compound naturally occurring in olives, may reduce blood sugar levels and promote weight loss.

This study could lead to the creation of affordable and safe natural products designed to help manage obesity and type 2 diabetes in humans. The researchers found that after just one week, obese mice with diabetes that were given oral elenolic acid weighed significantly less and showed better blood sugar (glucose) regulation than before treatment and compared to control obese mice not receiving elenolic acid. The glucose-lowering effect was comparable with that of the injectable diabetic medication liraglutide and better than metformin, one of the most common oral medicines for type 2 d.