Matthew Perry’s devastating final words have been revealed as five people have been charged in connection with his death. The Friends actor passed away in October aged 54 from drowning and the ‘acute effects’ of horse tranquiliser ketamine. A police investigation into what led to his death is ongoing, with five people – including two doctors, a woman dubbed ‘the ketamine queen’ and the late star’s personal assistant – being charged.

Perry’s former long-term live-in assistant has said Perry told him on the night of his death to ‘shoot me up with a big one’. He also admitted in court documents he injected the star with three doses of the drug in his final hours. Kenneth Iwamasa, 59, made the confession in a set of plea agreement papers he signed after he and four others were arrested in connection with supplying the drugs that killed the actor.

The papers show the injections were administered by non-medically trained Iwamasa from 8.30am on the day Matthew died in the hot tub of his Pacific Palisades mansion in Los Angeles. After the first dose, the papers say Perry’s assistant gave him another one four hours later.

He then reportedly gave him another 40 minutes later. It was before the third injection Perry allegedly told him: ‘Shoot me up with a big one.’ The actor is said to have then told Iwamasa to start up the hot tub where his assistant later found him dead with his head in the water after his employee went to run a set of errands.

Perry’s fi.