Harvey Levin, founder and host of TMZ, explains the alleged ties between Brooke Mueller and Perry and what this could mean to the investigation into the actor's death. The plea agreement given to Matthew Perry's assistant revealed details of the actor's final hours and the two months leading up to his tragic death. Authorities arrested five people Thursday in Perry's Oct.

28 death. On the morning of Oct. 28, Perry's assistant, Kenneth Iwamasa, administered a shot of ketamine to the actor around 8:30 a.

m. By 12:45 p.m.

, Perry had instructed Iwamasa to give him another injection while the "Friends" star watched a movie. Roughly 40 minutes later, Perry requested another injection, allegedly telling Iwamasa, "Shoot me up with a big one," according to the plea agreement. MATTHEW PERRY DEATH PROBE REVEALS ACTOR WAS MANIPULATED BY ‘LEECHES’ IN HIS INNER CIRCLE Matthew Perry's final hours were revealed in a plea agreement.

(Gregg DeGuire) The live-in assistant administered a third injection to Perry while the 54-year-old was near or in a Jacuzzi. Iwamasa then left the home to run errands for Perry. When he returned home, the assistant found Perry "face down" in the Jacuzzi, deceased.

Perry was introduced to Dr. Salvador Plasencia, a ketamine source, in September by Iwamasa. Plasencia, who obtained ketamine from Dr.

Mark Chavez, allegedly taught the assistant how to inject Perry with ketamine. Chavez previously ran a ketamine clinic and allegedly submitted a bogus prescription in .