The study showed that females with heavy cannabis use had a more than 1.5-fold higher risk of cardiovascular disease mortality compared to nonusers. After comprehensive adjustments to exclude other influencing factors, it was found that the risks for all-cause mortality, cardiovascular disease mortality, and cancer mortality in women increased by 49 percent, 167 percent, and 61 percent, respectively.

These risks increased by 28 percent, zero percent, and 9 percent for men, respectively. This suggests that heavy cannabis use has a greater impact on mortality risk for women, particularly with a significant increase in the risk of cardiovascular disease mortality. Additionally, the data revealed that those with heavy cannabis use tend to be younger and more likely to smoke, but they exhibit lower levels of alcohol use, hypertension (high blood pressure), dyslipidemia (abnormal lipid levels), obesity, and diabetes.

They also tend to have lower levels of education and income. Further analysis showed that overweight women with heavy cannabis use had significantly increased risks of all-cause mortality and cancer mortality—by 123 percent and 179 percent, respectively. For women without hypertension, these risks increased by 114 percent and 143 percent, respectively.

Additionally, women without diabetes experienced a nearly twofold (192 percent) increase in the risk of cardiovascular disease mortality. In contrast to the previously mentioned study, this research evaluated the impac.