In a recent study published in the Environmental Health Perspectives , researchers investigated the association between midlife residential greenness and cognitive decline later in life, considering the effects of apolipoprotein E (APOE)-ɛ4 status, socioeconomic status, and rural/urban residency. Study: Midlife Residential Greenness and Late-Life Cognitive Decline among Nurses’ Health Study Participants . Image Credit: CandyBox Images/Shutterstock.

com Background Alzheimer’s disease and related dementia (ADRD) (a group of brain disorders that cause memory loss and cognitive decline) can begin decades before symptoms appear, with cognitive decline being a key aspect. Research into novel risk factors for cognitive decline is crucial for dementia prevention. Studies suggest residential greenness may improve cognitive function through stress reduction, attention restoration, lower air pollution, increased physical activity, and social connection.

However, most studies are cross-sectional. Midlife risk factors like psychological stress, vascular issues, and physical inactivity strongly influence dementia risk. The APOE-ɛ4 allele is a significant genetic risk factor.

Further research is needed to confirm the longitudinal association between midlife residential greenness and cognitive decline and to identify the most effective interventions for different populations, including APOE-ɛ4 carriers and socioeconomically disadvantaged groups. About the study The Nurses’ Health Stu.