A recent study published in the journal Cell Reports Medicine compares the effects of a ketogenic diet with reduced free sugar intake on cardiometabolic health. Study: Ketogenic diet but not free-sugar restriction alters glucose tolerance, lipid metabolism, peripheral tissue phenotype, and gut microbiome: RCT. Image Credit: Sea Wave / Shutterstock.
com Free-sugar restriction Many modern and natural sweet foods contain free sugars like glucose and fructose. Restricting free sugar to less than 5% of total energy intake can reduce energy intake by 100 kcal/ day. However, this approach has not been shown to reduce fat mass.
An earlier study by the current study's authors did not identify any significant change in energy balance within 24 hours of free-sugar restriction. This discrepancy may be due to other factors in the energy cycle or inaccurate self-reporting of energy intake. Carbohydrate restriction The ketogenic diet involves reducing carbohydrate intake for weight loss and altering one’s metabolism.
These effects are attributed to the hepatic production of ketone bodies as fuel for peripheral tissues. Previous studies suggest that the ketogenic diet reduces physical activity energy expenditure (PAEE) levels compared to high-carbohydrate diets. Nevertheless, how the ketogenic diet affects the energy cycle and cardiometabolic health remains unclear.
Energy metabolism in skeletal muscle and fatty tissue can be affected by physical activity and nutrition. The gut microbiome ,.