On the occasion of World AIDS Day on 1 December 2024, the International Antiviral (formerly AIDS) Society-USA (IAS-USA) has published new international guidelines for the treatment and prevention of HIV. The updated recommendations were developed by a panel of volunteer medical experts, including Prof Clara Lehmann of the University Hospital Cologne and the German Center for Infection Research (DZIF). They are based on significant advances in antiretroviral therapies and new prevention strategies such as pre-exposure prophylaxis.

The 2024 guidelines highlight the significant progress made in the fight against HIV while recognising that there is still much to be done to ensure equitable access to life-saving interventions. Thanks to effective antiretroviral therapy, many people living with HIV can achieve a normal or near-normal life expectancy. As new data and new antiretroviral drugs and formulations become available, recommendations for HIV treatment, clinical management and prevention need to be regularly updated so that healthcare professionals can provide the best care for their patients.

An international panel of leading experts in HIV research and clinical care identified and reviewed the latest evidence from peer-reviewed literature and conference presentations published between June 2022 and October 2024, as well as data provided by antiretroviral manufacturers. Expert consensus based on the comprehensive review resulted in updated guidelines for the treatment and pr.