Hospitals across the U.S. are taking steps to conserve their supplies of IV fluids after Hurricane Helene struck a critical manufacturing plant belonging to the country’s biggest supplier.

Baxter International, a medical technology company responsible for making IV fluids for most U.S. hospitals, said Sunday that it would temporarily close production at its North Cove, North Carolina-based facility because of flooding from Helene , raising concerns about a potential nationwide shortage.

IV fluids are used to deliver drugs or water with electrolytes directly into a patient’s bloodstream. They’re also critical for surgery, when a person is unable to eat or drink, to keep them hydrated. Baxter also makes specialty fluids, such as peritoneal dialysis fluid, which helps patients with kidney failure filter waste from their blood, as well as irrigation fluids, used during procedures to clean or flush wounds.

Follow live updates on the aftermath of Hurricane Helene There are four primary manufacturers of IV fluids in the U.S. Baxter is the leader, accounting for about 60% of the market.

The company is the main supplier for Mass General Brigham in Boston, which uses more than 100,000 liters of IV fluid from Baxter every month. On a call Thursday with reporters, Dr. Paul Biddinger, Mass General’s chief preparedness and continuity officer, said the health system received a letter from Baxter that said that due to the temporary closure, the system would receive only 40% of its us.