Announcing a new article publication for Cardiovascular Innovations and Applications journal. Recent advancements in immunotherapy have substantially improved overall survival and quality of life among patients with cancer. Notably, immune checkpoint inhibitors (ICIs) have emerged as a revolutionary strategy, particularly in the management of advanced cancers.
However, the success of ICIs is accompanied by the challenge of immune-related adverse events. Although rare, cardiovascular adverse events associated with ICIs are associated with high fatality rates and rapid clinical progression, thereby necessitating timely intervention. This review article explores the histopathologic characteristics of ICI-induced myocarditis, shedding light on the complexities of diagnosis and management.
Several studies examining the histopathologic features of ICI-induced myocarditis have emphasized the roles of macrophages and the potential utility of ancillary tests such as immunohistochemistry. Quantifying CD68+ macrophage abundance may enhance diagnostic sensitivity, thereby providing valuable insights into clinical outcomes. Related Stories Exploring the role of diet and supplements in cancer prevention New nanoparticle-based immunotherapy delays hormone therapy resistance in prostate cancer New treatment option for endometrial cancer shows promise in phase II trial In conclusion, the need for a nuanced approach to diagnosing ICI-induced myocarditis is emphasized.
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