The new season of Grey’s Anatomy will feature trademark “shocking moments”, a showrunner announced. Cast members from the longest-running TV medical drama appeared during a D23 panel to celebrate two decades of the show. Speaking about the 21st season airing in September, showrunner Meg Marinis said: “My favourite thing to do is to tie up our characters in the messiest knot possible in a finale, which I feel like we did pretty successfully.

“We have doctors who do not have jobs, and we pick up pretty close to where we ended after the finale, and we’re going to see how and if those doctors get their jobs back.” She also teased that there will be “some fun relationships that kick off right in the premiere”, alongside some “very Grey’s Anatomy shocking moments”. The original show line-up was led by actress Ellen Pompeo, alongside Chandra Wilson and James Pickens Jr who reflected on their memories shooting the 2005 pilot episode.

“I was just happy to pay my credit card bill,” Wilson, who plays Miranda Bailey, joked. “My first day on Grey’s was the day that I gave the ‘I have five rules’ speech. “I hadn’t met any of the babies, they didn’t meet me until I gave that speech,” she said, referring to the interns played by Pompeo, Sandra Oh, Justin Chambers, Katherine Heigl and TR Knight.

Meanwhile Pickens Jr recalled meeting creator Shonda Rhimes during an audition callback, before producer James Parriott told him: “I’ll tell you somethi.