Current box office ‘it’ man Glen Powell (“Twisters,” “Hit Man”) has been tapped to guest star on the first of two “Family Guy” holiday specials set to run exclusively on Hulu. In a Halloween-themed episode that will premiere on October 14, Powell will play “Patrick McCloskey,” the reigning champion in Quahog’s annual Pumpkin Contest. Also guesting on that episode: Derek Jacobi (“Gosford Park,” “Gladiator”) as the voice of Stewie’s beloved teddy bear, “Rupert.

” Per the logline, the Halloween episode follows Peter and his friends as they “aim to unseat the reigning champion (Glen Powell) in Quahog’s annual Pumpkin Contest by any means necessary.” The Powell and Jacobi castings were announced Saturday during the “Family Guy” panel at San Diego Comic-Con . (After the Halloween special will be a Christmas event as well.

) “Family Guy” voice stars including Alex Borstein (who came out with a “Saggy Naggy” Lois Griffin doll, available for purchase on the Comic-Con floor), Seth Green, Jennifer Tilly, Gary Cole and Mike Henry joined executive producers Rich Appel, Alec Sulkin, Steve Callaghan and Kara Vallow for the panel, which celebrated the 25th anniversary of the series. The Halloween episode will help fans bide the time as Fox waits until midseason to bring “ Family Guy ” back for Season 23. (That marks the first time the animated staple hasn’t been on the network’s fall schedule since 2005 — when it returned to the a.