Females' and males' muscles differ in glucose and fatty acid handling—but regular physical activity quickly triggers similar beneficial metabolic changes in the muscles of both sexes, new research to be presented at the (EASD) (Madrid, 9–13 September) has found. Exercise has a potent effect on and is the most effective strategy to prevent weight-loss-related muscle loss and type 2 . The first author of the study, Dr.
Simon Dreher, of the Institute for Clinical Chemistry and Patho biochemistry, University of Tübingen, and Institute for Diabetes Research and Metabolic Diseases, Helmholtz Munich in Tübingen, Germany, says, "Exercise preserves in healthy individuals and restores it in those with pre-diabetes or diabetes. However, there are sex-related differences in how skeletal muscle uses glucose and lipids. "A greater understanding of how the underlying molecular differences between the skeletal muscles of females and males affect their response to exercise could provide valuable insight into how to tailor exercise recommendations to more effectively prevent or delay the progression of type 2 diabetes.
It could also help with the prevention of obesity." To learn more, Dr. Dreher and colleagues analyzed the molecular differences in from nine males and 16 females.
All were healthy, with an average age of 30 years, living with overweight or obesity and did not take part in regular sporting activities. The participants performed one hour of moderate to intense endurance ex.