Aging is a that no one can avoid. Ideally, growing old should be a time to relax and enjoy the fruits of your labor. Aging also has a darker side, however, often linked to disease.
Every second, your cells perform billions of biochemical reactions that fuel essential functions for life, forming a highly interconnected . This network enables cells to grow, proliferate and repair themselves, . But does aging cause metabolic decline, or does metabolic disruption accelerate aging? Or both? To address this chicken-or-egg question, you first need to understand how metabolic processes break down during aging and disease.
I am a , and focuses on exploring the complex relationship between metabolism, stress and aging. Ultimately, we hope this work will provide strategies to promote healthier aging and more vibrant lives. Aging is the most significant risk factor for many of society's , including , , cardiovascular disease and neurodegenerative disorders.
A key factor behind the onset of these health issues is the disruption of cellular and metabolic . Disrupting homeostasis destabilizes the body's internal environment, leading to imbalances that can trigger a cascade of health issues, including metabolic disorders, chronic diseases and impaired cellular functions that contribute to aging and other serious conditions. Disrupted metabolism is linked to many hallmarks of aging cells, such as , which is damage to the protective ends of chromosomes, and , the tendency to form genetic mutat.