Does cannabis use disorder increase the risk of head and neck cancer?

A recent study published in JAMA Otolaryngology Head & Neck Surgery determines whether cannabis use disorder (CUD) increases the risk of head and neck cancer (HNC). Study: Cannabis Use and Head and Neck Cancer. Image Credit: Andry Jeymsss / Shutterstock.

com What is HNC? HNC is the sixth leading cause of cancer throughout the world. In 2020, over 870,000 HNC cases were reported globally, 440,000 of which resulted in death. In the United States, HNC is responsible for about 3% of all cancers and over 1.

5% of cancer-related deaths. HNC can be further categorized based on the different tissues affected, some of which include the oral cavity, pharynx, larynx, and adjacent salivary glands. HNC has historically been caused by tobacco use and drinking; however, a significant proportion of HNC cases are also caused by human papillomavirus (HPV) infection.

Cannabis risk Throughout both the U.S. and the rest of the world, cannabis is the most commonly used illicit substance.

Cannabis is most commonly consumed through inhalation for both recreational and medical purposes, the latter of which may include amelioration of nausea, cancer pain, and anorexia. Despite its potential therapeutic effects for these conditions, cannabis use remains controversial, as it may increase the risk of developing psychotic disorders and cognitive defects. Furthermore, the smoke content of cannabis contains carcinogens similar to those found in cannabis, such as polycyclic aromatic hydrocarbons (PAHs) and nit.