Scientists discovered a neural activity pattern as a biomarker for monitoring OCD patients treated with DBS, revealing how neural signatures predict and reflect treatment outcomes. This method provides real-world insights into patient responses, enhancing therapy personalization and accessibility. Credit: SciTechDaily.
com Researchers identified a neural activity pattern that serves as a biomarker in OCD treatment via deep brain stimulation, enabling better monitoring and personalization of therapy based on real-time brain activity. A recent study, published in Nature Medicine , has identified a specific neural activity pattern as a novel biomarker to accurately predict and monitor the clinical status of individuals with obsessive-compulsive disorder (OCD) who have undergone deep brain stimulation (DBS), a rapidly emerging therapeutic approach for severe psychiatric disorders. The study, from Baylor College of Medicine and Texas Children’s Hospital, was led by led by Drs.
Sameer Sheth and Wayne Goodman along with co-lead authors, Drs. Nicole Provenza, Sandy Reddy, and Anthony Allam. “Recent advances in surgical neuromodulation have enabled long-term continuous monitoring of brain activity in OCD patients during their everyday lives,” said Dr.
Nicole Provenza, an assistant professor at Baylor College of Medicine and McNair Scholar. “We used this novel opportunity to identify key neural signatures that can act as predictors of clinical state in twelve individuals with tr.