The Triangulation of Innovative Methods to End Alzheimer's Disease project will use large, diverse datasets to examine whether interventions targeting alcohol use, depression, vision or hearing impairments, or social isolation can protect people from Alzheimer's disease and related dementias. This project is a collaboration among Dr. Maria Glymour at Boston University School of Public Health, Dr.

Jacqueline Torres at the University of California, San Francisco and Dr. Paola Gilsanz at the Kaiser Permanente Northern California Division of Research and colleagues at three other research institutions. Up to 45 percent of Alzheimer's disease and related dementias (ADRD) cases could be prevented by modifiable risk factors, but current research is limited to observational studies that make it difficult to establish definitive causes.

Dr. Maria Glymour, chair and professor of epidemiology at Boston University School of Public Health (BUSPH), Dr. Jacqueline Torres, associate professor, epidemiology & biostatistics at the University of California, San Francisco, and Dr.

Paola Gilsanz, research scientist II at the Kaiser Permanente Northern California Division of Research, have received a $28.8 million grant from the National Institute on Aging to lead an ambitious initiative that will strengthen this research and develop more reliable evidence to guide prevention and treatment strategies for these degenerative neurological diseases. The five-year award will support the Triangulation o.