In a recent study published in Scientific Reports , researchers conducted a placebo-controlled, double-blind crossover field trial to examine whether the phytocannabinoid cannabigerol impacted mood, stress, and anxiety and caused any related adverse effects of cognitive or motor impairment. Study: Acute effects of cannabigerol on anxiety, stress, and mood: a double-blind, placebo-controlled, crossover, field trial . Image Credit: Dmytro Tyshchenko/Shutterstock.
com Background With the legalization of cannabis in various countries, cannabis growers are attempting to diversify their produce to meet the growing interest of cannabis consumers. While delta-9-tetrahydrocannabinol, or THC, continues to be the main molecule of interest among cannabis users for its intoxicating effects, there is also a growing interest in some of the other non-intoxicating compounds in cannabis for their medicinal and analgesic effects. However, this has also resulted in the unregulated isolation and marketing of various terpenes and phytocannabinoids as therapeutic compounds, although the therapeutic value remains unsubstantiated.
While cannabidiol is the major non-intoxicating compound isolated from cannabis, cannabigerol is becoming increasingly popular. The acidic form of cannabigerol, cannabigerolic acid, is the precursor to various phytocannabinoids, including cannabidiol and THC. Studies using animal models have found that cannabigerol shows broad-spectrum therapeutic properties such as antifung.