Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig’s disease and, in Europe, Charcot’s disease is a serious neurodegenerative disorder characterized by the progressive weakening and wasting of muscles. ALS slowly takes away the ability to walk, eat, and breathe. ALS symptoms can be categorized by their initial onset or significance in supporting a diagnosis.

The Essential Guide to Parkinson’s Disease: Symptoms, Causes, Treatments, and Natural Remedies Multiple Sclerosis: Symptoms, Causes, Treatments, and Natural Approaches Crohn’s Disease: Symptoms, Causes, Treatments, and Natural Approaches Weakness in the ankle, finger, or upper arm Muscle atrophy, especially around the thumb Muscle twitches and cramps in a weak limb Loss of coordination Slow or slurred speech Vocal pitch changes Weakness in the neck muscles Difficulty swallowing or chewing, with possible weight loss or malnutrition Coughing while drinking water Excessive saliva or mucus, causing drooling or frequent throat-clearing Twitches or atrophy of the tongue Changes in cognitive function Intense and rapid mood swings Sudden, uncontrollable episodes of crying or laughing, disproportionate to the situation Progressive, unintentional weight loss Difficulty walking or unexplained falls Difficulty breathing when lying flat (orthopnea) Weakness in one side of the diaphragm (hemidiaphragm weakness) Speech that weakens or worsens at the end of the day Exaggerated reflexes (hyperreflexia) with muscle l.