Researchers discovered that lower folate intake may enhance metabolic health and promote healthier aging in animal models, challenging the established belief that high folate consumption is universally beneficial. The study suggests that optimal folate levels might vary with age, advocating for tailored dietary guidelines. In a study published in Life Science Alliance , scientists from Texas A&M AgriLife Research discovered that reducing folate intake can promote healthier metabolisms in aging animal models.

This finding challenges the traditional belief that high folate consumption is universally beneficial for health. The study was led by Michael Polymenis, Ph.D.

, professor and associate head of graduate programs in the Texas A&M College of Agriculture and Life Sciences Department of Biochemistry and Biophysics. Michael Polymenis, Ph.D.

, principal investigator, and Heidi Blank, Ph.D., first author of the study published in Life Science Alliance .

This is the latest study by the researchers in their continuous investigation of the effects of folate in biological models. (Eun-Gyu No, Ph.D.

/Texas A&M AgriLife) Folate, a B vitamin essential for cell growth and development, is widely recognized for its role in preventing birth defects. It’s found naturally in foods like leafy greens, and it is typically added to refined grains. Despite its prevalence, the long-term health implications of consuming high amounts of folate throughout life are unclear.

By limiting folate in animal.