Seattle (4-5) at San Francisco (5-4) Sunday, 4:05 p.m. EST, Fox BetMGM NFL odds: 49ers by 6 1/2.

Against the spread: Seahawks 2-6-1; 49ers 4-5. Series record: Seahawks lead 30-23. Last meeting: 49ers beat Seahawks 36-24 in Seattle on Oct.

10. Last week: Seahawks had bye last week, lost 26-20 in OT to Rams on Nov. 3; 49ers beat the Buccaneers 23-20.

Seahawks offense: overall (9), rush (27), pass (1), scoring (15). Seahawks defense: overall (25), rush (26), pass (20), scoring (23). 49ers offense: overall (2), rush (5), pass (2), scoring (7).

49ers defense: overall (9), rush (8), pass (12), scoring (17). Turnover differential: Seahawks minus-6; 49ers plus-3. WR DK Metcalf is expected to return this week after missing each of the past two games with an MCL sprain.

Metcalf injured his knee in Seattle’s win over Atlanta on Oct. 20. Though he has missed two games, Metcalf leads Seattle with 568 receiving yards on 35 receptions this season.

QB Brock Purdy threw for 353 yards and two TDs last week against Tampa Bay and had his 13th career game with a rating of at least 115. Purdy has won all five starts in his career against Seattle, including a playoff win, with his 118.0 rating in those games the best of any QB who has started at least five games against the Seahawks.

Special teams. There were several big plays on special teams in the first meeting between the teams with Seattle's Laviska Shenault Jr. losing a fumble on a kick return and then returning another kick 97 yards for a .