The 7-2 Buffalo Bills are gearing up for an important matchup against the 4-5 Indianapolis Colts, but once again, injuries are stealing the spotlight. The biggest headline is the absence of rookie sensation Keon Coleman, who’s sidelined with a wrist injury. It seems the Bills’ are suffering from a sudden epidemic of weak wrists, as newly acquired star Amari Cooper may also be unavailable due to a similar issue.

Perhaps these guys missed out on enough breast milk as babies—clearly, the wrist bones didn’t get the memo to grow strong! With key players like Coleman and Cooper possibly out, the question is: can the Bills overcome these setbacks and still get the win? Let’s hope so— can’t let Colts Mafia be singing “Go Colts, neeigh”! On Saturday night, the Buffalo Bills elevated wide receivers Tyrell Shavers and K.J. Hamler from their practice squad, which implies Amari Cooper will likely sit.

Meanwhile, the team faces further injury challenges as LB Baylon Spector (calf) and Dawuane Smoot (wrist) joined the growing list of players on injured reserve this week, which already includes LB Matt Milano, DT DeWayne Carter, and OT Tylan Grable. While the injury report for the Indianapolis Colts is far cleaner than the Buffalo Bills’, they will still be missing some key pieces for this matchup. The Colts will be without starting center Ryan Kelly , who’s been placed on injured reserve, and wide receiver Michael Pittman Jr.

, who has been ruled out for the game. WR Ke.